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Peroxisome proliferator-activated receptor gamma

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Peroxisome proliferator-activated receptor gamma - Wikipedia

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Existing User Sign In. New to Read Sign Up. PPARa agonists have been reported to reduce blood pressure in clinical trials in humans.

PPARs (Peroxisome Proliferator-Activated Receptors)

The effect of PPARa agonist on renal vasodilation, sodium excretion and excretion of urinary epoxygenase or monooxygenase products in response to salt loading is not known. The regulation of urinary HETE excretion may be impaired in human hypertension. Other Name: Tricor Drug: Placebo Subjects will be randomized to receive placebo or fenofibrate for five days by mouth Placebo Comparator: Fenofibrate, then placebo Randomized study of fenofibrate versus placebo during high salt intake.

Participants were classified as salt-sensitive if the average study day mean arterial pressure MAP was at least 5 mmHg higher during the high salt placebo arm than during low salt intake. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision.

Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.

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Save this study. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Federal Government.

nutritiony.com/2744-viber-tracking-for.php Read our disclaimer for details. Results First Posted : June 20, Last Update Posted : June 28, Study Description. The hypothesis is to test to see if the drug fenofibrate will increase important chemicals in the body and specifically in the kidney, help to rid the body of salt by the kidneys, decrease blood pressure and improve insulin sensitivity during high-salt intake in individuals with hypertension. MedlinePlus related topics: Sodium. Drug Information available for: Fenofibrate. FDA Resources. Arms and Interventions. Subjects will be randomized to receive placebo or fenofibrate for five days by mouth.

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Randomized study of fenofibrate versus placebo during high salt intake. Outcome Measures. Eligibility Criteria. Contacts and Locations.

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Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.